GSE76425 IKZF1 CRBN MEIS2 IKZF3 inhibition Lenalidomide 1 v 10 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE76425_IKZF1_CRBN_MEIS2_IKZF3 inhibition_Lenalidomide_1_v_10_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE76425_IKZF1_CRBN_MEIS2_IKZF3 inhibition_Lenalidomide_1_v_10_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE76425_IKZF1_CRBN_MEIS2_IKZF3 inhibition_Lenalidomide_1_v_10_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE76425_IKZF1_CRBN_MEIS2_IKZF3 inhibition_Lenalidomide_1_v_10_human_up.

Results found

Linked to

	Label	Description
	NR1H3 Gene (Entity type)	ENSG00000025434 - nuclear receptor subfamily 1 group H member 3
	ADAM8 Gene (Entity type)	ENSG00000151651 - ADAM metallopeptidase domain 8
	MYBPC2 Gene (Entity type)	ENSG00000086967 - myosin binding protein C2
	EFEMP2 Gene (Entity type)	ENSG00000172638 - EGF-like fibulin extracellular matrix protein 2
	RBM5 Gene (Entity type)	ENSG00000003756 - RNA binding motif protein 5
	TOR3A Gene (Entity type)	ENSG00000186283 - torsin family 3 member A
	DOK4 Gene (Entity type)	ENSG00000125170 - docking protein 4
	THBS3 Gene (Entity type)	ENSG00000169231 - thrombospondin 3
	TRAK2 Gene (Entity type)	ENSG00000115993 - trafficking kinesin protein 2
	TTC9 Gene (Entity type)	ENSG00000133985 - tetratricopeptide repeat domain 9

NR1H3

Gene (Entity type)

ENSG00000025434 - nuclear receptor subfamily 1 group H member 3

ADAM8

Gene (Entity type)

ENSG00000151651 - ADAM metallopeptidase domain 8

MYBPC2

Gene (Entity type)

ENSG00000086967 - myosin binding protein C2

EFEMP2

Gene (Entity type)

ENSG00000172638 - EGF-like fibulin extracellular matrix protein 2

RBM5

Gene (Entity type)

ENSG00000003756 - RNA binding motif protein 5

TOR3A

Gene (Entity type)

ENSG00000186283 - torsin family 3 member A

DOK4

Gene (Entity type)

ENSG00000125170 - docking protein 4

THBS3

Gene (Entity type)

ENSG00000169231 - thrombospondin 3

TRAK2

Gene (Entity type)

ENSG00000115993 - trafficking kinesin protein 2

TTC9

Gene (Entity type)

ENSG00000133985 - tetratricopeptide repeat domain 9

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.