Synonyms:ADAM metallopeptidase domain 8, ADAM8, CD156, CD156a, ENTREZ:101, HGNC:215, MIM:602267, MS2, NM_001109, NM_001164489, NM_001164490, NP_001100, NP_001157961, NP_001157962, XM_011539117, XM_017015465, XM_017015466, XP_011537419, XP_016870954, XP_016870955
Omim:OMIM:602267
Id:6a12ebce-85cf-5357-8bba-02f449f37e07
Hgnc:HGNC:215
Description:ADAM metallopeptidase domain 8
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]