Synonyms:ENTREZ:10181, G15, H37, HGNC:9902, LUCA-15, LUCA15, MIM:606884, NM_005778, NP_005769, NR_036627, RBM5, RMB5, RNA binding motif protein 5, XM_006712917, XM_011533261, XM_011533262, XM_017005503, XM_017005504, XM_017005505, XM_024453289, XM_024453290, XP_006712980, XP_011531563, XP_011531564, XP_016860992, XP_016860993, XP_016860994, XP_024309057, XP_024309058, XR_427245
Omim:OMIM:606884
Id:ENSG00000003756
Hgnc:HGNC:9902
Description:RNA binding motif protein 5
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011]