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GTF2A1L (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ALF, ENTREZ:11036, GTF2A1L, HGNC:30727, MIM:605358, NM_001193487, NM_006872, NM_172196, NP_001180416, NP_006863, general transcription factor IIA subunit 1 like
Omim:OMIM:605358
Id:ENSG00000242441
Hgnc:HGNC:30727
Entrez:11036
Ensembl:ENSG00000242441
Description:general transcription factor IIA subunit 1 like
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GTF2A1L's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GTF2A1L.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GTF2A1L.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GTF2A1L.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GTF2A1L.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE179235 MEK NRAS inhibition 2 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE179235 MEK NRAS inhibition 5 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE179235 MEK NRAS inhibition 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE210655 3 V 0 CISPLATIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE139540 menadione 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE197571 FOXM1 RNF112 overexpression MGC-803 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE179235 MEK NRAS inhibition 4 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE100148 EZH2 inhibition 0 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE112202 digoxin 5 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE179235 MEK NRAS inhibition 2 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE179235 MEK NRAS inhibition 5 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE179235 MEK NRAS inhibition 0 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE210655 3 V 0 CISPLATIN MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE139540 menadione 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE197571 FOXM1 RNF112 overexpression MGC-803 3 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE179235 MEK NRAS inhibition 4 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE100148 EZH2 inhibition 0 v 5 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE112202 digoxin 5 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE85880 GSE85881 tretinoin cardiac muscle cell 4 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.