GSE179235 MEK NRAS inhibition 0 v 6 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE179235_MEK_NRAS inhibition_0_v_6_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE179235_MEK_NRAS inhibition_0_v_6_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE179235_MEK_NRAS inhibition_0_v_6_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE179235_MEK_NRAS inhibition_0_v_6_human_up.

Results found

Linked to

	Label	Description
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	CISH Gene (Entity type)	ENSG00000114737 - cytokine inducible SH2 containing protein
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2
	HDAC5 Gene (Entity type)	ENSG00000108840 - histone deacetylase 5
	NDUFB1 Gene (Entity type)	ENSG00000183648 - NADH:ubiquinone oxidoreductase subunit B1
	THRA Gene (Entity type)	ENSG00000126351 - thyroid hormone receptor alpha
	ULK1 Gene (Entity type)	ENSG00000177169 - unc-51 like autophagy activating kinase 1
	TRAF1 Gene (Entity type)	ENSG00000056558 - TNF receptor associated factor 1
	MANBA Gene (Entity type)	ENSG00000109323 - mannosidase beta

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

CISH

Gene (Entity type)

ENSG00000114737 - cytokine inducible SH2 containing protein

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

HDAC5

Gene (Entity type)

ENSG00000108840 - histone deacetylase 5

NDUFB1

Gene (Entity type)

ENSG00000183648 - NADH:ubiquinone oxidoreductase subunit B1

THRA

Gene (Entity type)

ENSG00000126351 - thyroid hormone receptor alpha

ULK1

Gene (Entity type)

ENSG00000177169 - unc-51 like autophagy activating kinase 1

TRAF1

Gene (Entity type)

ENSG00000056558 - TNF receptor associated factor 1

MANBA

Gene (Entity type)

ENSG00000109323 - mannosidase beta

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.