DEFB4A (Gene)

Organism:

Homo sapiens

Synonyms:BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, DEFB4A, DEFB4B, DEFB4P, ENTREZ:100289462, ENTREZ:1673, HBD-2, HGNC:2767, HGNC:30193, MIM:602215, NM_001205266, NM_004942, NP_001192195, NP_004933, SAP1, defensin beta 4A, defensin beta 4B

Omim:OMIM:602215

Id:ENSG00000171711

Hgnc:HGNC:2767

Entrez:1673

Ensembl:ENSG00000171711

Description:defensin beta 4A

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DEFB4A's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with DEFB4A.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DEFB4A.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DEFB4A.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DEFB4A.

Results found

Linked to

	Label	Description
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	T66-Lung Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE135030 11 V 4 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE125956 SYK knockdown 3 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE228357 OGA knockdown 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 ruxolitinib 1 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 1 V 3 RUXOLITINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE228357 OGA knockdown 3 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	ACSM2A Down Gene Set (Entity type)	A Gene Set from LINCS
	PLAGL1 Down Gene Set (Entity type)	A Gene Set from LINCS

GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

T66-Lung Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE135030 11 V 4 FLUDARABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE125956 SYK knockdown 3 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE228357 OGA knockdown 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 ruxolitinib 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 1 V 3 RUXOLITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE228357 OGA knockdown 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

ACSM2A Down

Gene Set (Entity type)

A Gene Set from LINCS

PLAGL1 Down

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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