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RBPJ (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:AOS3, CBF-1, CBF1, ENTREZ:3516, HGNC:5724, IGKJRB, IGKJRB1, KBF2, MIM:147183, NM_001363577, NM_001374400, NM_001374401, NM_001374402, NM_001374403, NM_001379406, NM_001379407, NM_001379408, NM_001379409, NM_005349, NM_015874, NM_203283, NM_203284, NP_001350506, NP_001361329, NP_001361330, NP_001361331, NP_001361332, NP_001366335, NP_001366336, NP_001366337, NP_001366338, NP_005340, NP_056958, NP_976028, NP_976029, RBP-J kappa, RBP-J, RBP-JK, RBPJ, RBPJK, RBPSUH, SUH, XM_011513840, XM_017008170, XM_017008171, XM_017008174, XP_011512142, XP_016863659, XP_016863660, XP_016863663, csl, recombination signal binding protein for immunoglobulin kappa J region
Omim:OMIM:147183
Nci:C114508
Id:ENSG00000168214
Hgnc:HGNC:5724
Entrez:3516
Ensembl:ENSG00000168214
Description:recombination signal binding protein for immunoglobulin kappa J region
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View RBPJ's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with RBPJ.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using RBPJ.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for RBPJ.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RBPJ.

Results found

Linked to

 

Label

Description

 

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Gene Set (Entity type)

A Gene Set from LINCS

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Gene Set (Entity type)

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GSE138937 Rad21 CTCF knockdown SLK 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE135350 2 V 4 DEXAMETHASONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216043 10 V 5 CISPLATIN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE220806 1 V 3 PROGESTERONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE199107 tryptophan 6 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE128240 0 V 1 CYCLOPHOSPHAMIDE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE146982 metformin 4 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125956 SYK knockdown 4 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE206931 WDR5 inhibition WIN 3 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE138937 Rad21 CTCF knockdown SLK 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.