PKN1 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PKN1 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PKN1 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PKN1 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PKN1 Up.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	SMAD4 Gene (Entity type)	ENSG00000141646 - SMAD family member 4
	FLI1 Gene (Entity type)	ENSG00000151702 - Fli-1 proto-oncogene, ETS transcription factor
	SLC35E3 Gene (Entity type)	ENSG00000175782 - solute carrier family 35 member E3
	FRAT2 Gene (Entity type)	ENSG00000181274 - FRAT regulator of Wnt signaling pathway 2
	PSMA3 Gene (Entity type)	ENSG00000100567 - proteasome 20S subunit alpha 3
	SP3 Gene (Entity type)	ENSG00000172845 - Sp3 transcription factor
	NCF4 Gene (Entity type)	ENSG00000100365 - neutrophil cytosolic factor 4
	ATP2C1 Gene (Entity type)	ENSG00000017260 - ATPase secretory pathway Ca2+ transporting 1
	KCTD9 Gene (Entity type)	ENSG00000104756 - potassium channel tetramerization domain containing 9

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

SMAD4

Gene (Entity type)

ENSG00000141646 - SMAD family member 4

FLI1

Gene (Entity type)

ENSG00000151702 - Fli-1 proto-oncogene, ETS transcription factor

SLC35E3

Gene (Entity type)

ENSG00000175782 - solute carrier family 35 member E3

FRAT2

Gene (Entity type)

ENSG00000181274 - FRAT regulator of Wnt signaling pathway 2

PSMA3

Gene (Entity type)

ENSG00000100567 - proteasome 20S subunit alpha 3

SP3

Gene (Entity type)

ENSG00000172845 - Sp3 transcription factor

NCF4

Gene (Entity type)

ENSG00000100365 - neutrophil cytosolic factor 4

ATP2C1

Gene (Entity type)

ENSG00000017260 - ATPase secretory pathway Ca2+ transporting 1

KCTD9

Gene (Entity type)

ENSG00000104756 - potassium channel tetramerization domain containing 9

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.