GSE179235 MEK NRAS inhibition 5 v 6 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE179235_MEK_NRAS inhibition_5_v_6_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE179235_MEK_NRAS inhibition_5_v_6_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE179235_MEK_NRAS inhibition_5_v_6_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE179235_MEK_NRAS inhibition_5_v_6_human_dn.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2
	POLA2 Gene (Entity type)	ENSG00000014138 - DNA polymerase alpha 2, accessory subunit
	SLC35A3 Gene (Entity type)	ENSG00000117620 - solute carrier family 35 member A3
	DCPS Gene (Entity type)	ENSG00000110063 - decapping enzyme, scavenger
	CHAF1B Gene (Entity type)	ENSG00000159259 - chromatin assembly factor 1 subunit B
	TNFRSF14 Gene (Entity type)	ENSG00000157873 - TNF receptor superfamily member 14
	TGFBR1 Gene (Entity type)	ENSG00000106799 - transforming growth factor beta receptor 1
	PKMYT1 Gene (Entity type)	ENSG00000127564 - protein kinase, membrane associated tyrosine/threonine 1
	GTF2H3 Gene (Entity type)	ENSG00000111358 - general transcription factor IIH subunit 3

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

POLA2

Gene (Entity type)

ENSG00000014138 - DNA polymerase alpha 2, accessory subunit

SLC35A3

Gene (Entity type)

ENSG00000117620 - solute carrier family 35 member A3

DCPS

Gene (Entity type)

ENSG00000110063 - decapping enzyme, scavenger

CHAF1B

Gene (Entity type)

ENSG00000159259 - chromatin assembly factor 1 subunit B

TNFRSF14

Gene (Entity type)

ENSG00000157873 - TNF receptor superfamily member 14

TGFBR1

Gene (Entity type)

ENSG00000106799 - transforming growth factor beta receptor 1

PKMYT1

Gene (Entity type)

ENSG00000127564 - protein kinase, membrane associated tyrosine/threonine 1

GTF2H3

Gene (Entity type)

ENSG00000111358 - general transcription factor IIH subunit 3

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.