Synonyms:ATAR, CD270, ENTREZ:8764, HGNC:11912, HVEA, HVEM, LIGHTR, MIM:602746, NM_001297605, NM_003820, NP_001284534, NP_003811, TNF receptor superfamily member 14, TNFRSF14, TR2, XM_006711019, XM_011542383, XM_017002718, XM_017002720, XP_006711082, XP_011540685, XP_016858207, XP_016858209, XR_001737511, XR_001737512, XR_001737513, XR_426638
Omim:OMIM:602746
Id:ENSG00000157873
Hgnc:HGNC:11912
Description:TNF receptor superfamily member 14
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]