GSE226249 pirfenidone HL 5 v 3 human up (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE226249_pirfenidone_HL_5_v_3_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE226249_pirfenidone_HL_5_v_3_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE226249_pirfenidone_HL_5_v_3_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE226249_pirfenidone_HL_5_v_3_human_up.

Results found

Linked to

	Label	Description
	PGRMC1 Gene (Entity type)	ENSG00000101856 - progesterone receptor membrane component 1
	CHMP2A Gene (Entity type)	ENSG00000130724 - charged multivesicular body protein 2A
	HDAC5 Gene (Entity type)	ENSG00000108840 - histone deacetylase 5
	TNFRSF14 Gene (Entity type)	ENSG00000157873 - TNF receptor superfamily member 14
	EIF4A2 Gene (Entity type)	ENSG00000156976 - eukaryotic translation initiation factor 4A2
	F8 Gene (Entity type)	ENSG00000185010 - coagulation factor VIII
	NR1H3 Gene (Entity type)	ENSG00000025434 - nuclear receptor subfamily 1 group H member 3
	SIK3 Gene (Entity type)	ENSG00000160584 - SIK family kinase 3
	LTBR Gene (Entity type)	ENSG00000111321 - lymphotoxin beta receptor
	MED28 Gene (Entity type)	ENSG00000118579 - mediator complex subunit 28

PGRMC1

Gene (Entity type)

ENSG00000101856 - progesterone receptor membrane component 1

CHMP2A

Gene (Entity type)

ENSG00000130724 - charged multivesicular body protein 2A

HDAC5

Gene (Entity type)

ENSG00000108840 - histone deacetylase 5

TNFRSF14

Gene (Entity type)

ENSG00000157873 - TNF receptor superfamily member 14

EIF4A2

Gene (Entity type)

ENSG00000156976 - eukaryotic translation initiation factor 4A2

Gene (Entity type)

ENSG00000185010 - coagulation factor VIII

NR1H3

Gene (Entity type)

ENSG00000025434 - nuclear receptor subfamily 1 group H member 3

SIK3

Gene (Entity type)

ENSG00000160584 - SIK family kinase 3

LTBR

Gene (Entity type)

ENSG00000111321 - lymphotoxin beta receptor

MED28

Gene (Entity type)

ENSG00000118579 - mediator complex subunit 28

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.