SPN Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SPN Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SPN Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SPN Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SPN Down.

Results found

Linked to

	Label	Description
	SMURF1 Gene (Entity type)	ENSG00000198742 - SMAD specific E3 ubiquitin protein ligase 1
	VPS4B Gene (Entity type)	ENSG00000119541 - vacuolar protein sorting 4 homolog B
	CASQ2 Gene (Entity type)	ENSG00000118729 - calsequestrin 2
	RUNX1T1 Gene (Entity type)	ENSG00000079102 - RUNX1 partner transcriptional co-repressor 1
	PLXDC1 Gene (Entity type)	ENSG00000161381 - plexin domain containing 1
	TRRAP Gene (Entity type)	ENSG00000196367 - transformation/transcription domain associated protein
	IFFO1 Gene (Entity type)	ENSG00000010295 - intermediate filament family orphan 1
	MEX3C Gene (Entity type)	ENSG00000176624 - mex-3 RNA binding family member C

SMURF1

Gene (Entity type)

ENSG00000198742 - SMAD specific E3 ubiquitin protein ligase 1

VPS4B

Gene (Entity type)

ENSG00000119541 - vacuolar protein sorting 4 homolog B

CASQ2

Gene (Entity type)

ENSG00000118729 - calsequestrin 2

RUNX1T1

Gene (Entity type)

ENSG00000079102 - RUNX1 partner transcriptional co-repressor 1

PLXDC1

Gene (Entity type)

ENSG00000161381 - plexin domain containing 1

TRRAP

Gene (Entity type)

ENSG00000196367 - transformation/transcription domain associated protein

IFFO1

Gene (Entity type)

ENSG00000010295 - intermediate filament family orphan 1

MEX3C

Gene (Entity type)

ENSG00000176624 - mex-3 RNA binding family member C

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.