CASQ2 (Gene)

Organism:

Homo sapiens

Synonyms:CASQ2, ENTREZ:845, HGNC:1513, MIM:114251, NM_001232, NP_001223, PDIB2, calsequestrin 2

Id:ENSG00000118729

Entrez:845

Description:calsequestrin 2

The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq, Jul 2008]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CASQ2's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CASQ2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CASQ2.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CASQ2.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CASQ2.

Results found

Linked to

	Label	Description
	GSE109285 3 V 2 GLUCAGON MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE125862 2 V 1 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE130396 8 V 6 NERATINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE130437 0 V 1 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE228106 0 V 4 PACLITAXEL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE153189 2 V 0 INTERFERON GAMMA MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE149632 dopamine 0 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE228106 3 V 4 PACLITAXEL HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE92965 0 V 1 TAMOXIFEN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE226114,GSE226116 2 V 0 DOXORUBICIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS

GSE109285 3 V 2 GLUCAGON MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE125862 2 V 1 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE130396 8 V 6 NERATINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE130437 0 V 1 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE228106 0 V 4 PACLITAXEL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE153189 2 V 0 INTERFERON GAMMA MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE149632 dopamine 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE228106 3 V 4 PACLITAXEL HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE92965 0 V 1 TAMOXIFEN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE226114,GSE226116 2 V 0 DOXORUBICIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.