MEF2D Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with MEF2D Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with MEF2D Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with MEF2D Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MEF2D Up.

Results found

Linked to

	Label	Description
	PSEN1 Gene (Entity type)	ENSG00000080815 - presenilin 1
	USP9X Gene (Entity type)	ENSG00000124486 - ubiquitin specific peptidase 9 X-linked
	UBAP2 Gene (Entity type)	ENSG00000137073 - ubiquitin associated protein 2
	NCKAP1L Gene (Entity type)	ENSG00000123338 - NCK associated protein 1 like
	TUG1 Gene (Entity type)	ENSG00000253352 - taurine up-regulated 1
	DVL3 Gene (Entity type)	ENSG00000161202 - dishevelled segment polarity protein 3
	KYAT3 Gene (Entity type)	ENSG00000137944 - kynurenine aminotransferase 3
	SMG7 Gene (Entity type)	ENSG00000116698 - SMG7 nonsense mediated mRNA decay factor
	HUWE1 Gene (Entity type)	ENSG00000086758 - HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
	TLK1 Gene (Entity type)	ENSG00000198586 - tousled like kinase 1

PSEN1

Gene (Entity type)

ENSG00000080815 - presenilin 1

USP9X

Gene (Entity type)

ENSG00000124486 - ubiquitin specific peptidase 9 X-linked

UBAP2

Gene (Entity type)

ENSG00000137073 - ubiquitin associated protein 2

NCKAP1L

Gene (Entity type)

ENSG00000123338 - NCK associated protein 1 like

TUG1

Gene (Entity type)

ENSG00000253352 - taurine up-regulated 1

DVL3

Gene (Entity type)

ENSG00000161202 - dishevelled segment polarity protein 3

KYAT3

Gene (Entity type)

ENSG00000137944 - kynurenine aminotransferase 3

SMG7

Gene (Entity type)

ENSG00000116698 - SMG7 nonsense mediated mRNA decay factor

HUWE1

Gene (Entity type)

ENSG00000086758 - HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1

TLK1

Gene (Entity type)

ENSG00000198586 - tousled like kinase 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.