LEP Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with LEP Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with LEP Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with LEP Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LEP Down.

Results found

Linked to

	Label	Description
	PHIP Gene (Entity type)	ENSG00000146247 - PHIP subunit of CUL4-Ring ligase complex
	OSBPL2 Gene (Entity type)	ENSG00000130703 - oxysterol binding protein like 2
	MAPK8IP3 Gene (Entity type)	ENSG00000138834 - mitogen-activated protein kinase 8 interacting protein 3
	USP9X Gene (Entity type)	ENSG00000124486 - ubiquitin specific peptidase 9 X-linked
	ZNF394 Gene (Entity type)	ENSG00000160908 - zinc finger protein 394
	UPK3B Gene (Entity type)	ENSG00000243566 - uroplakin 3B

PHIP

Gene (Entity type)

ENSG00000146247 - PHIP subunit of CUL4-Ring ligase complex

OSBPL2

Gene (Entity type)

ENSG00000130703 - oxysterol binding protein like 2

MAPK8IP3

Gene (Entity type)

ENSG00000138834 - mitogen-activated protein kinase 8 interacting protein 3

USP9X

Gene (Entity type)

ENSG00000124486 - ubiquitin specific peptidase 9 X-linked

ZNF394

Gene (Entity type)

ENSG00000160908 - zinc finger protein 394

UPK3B

Gene (Entity type)

ENSG00000243566 - uroplakin 3B

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CFDE Workbench

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.