Synonyms:BRWD2, CHUJANS, DCAF14, DIDOD, ENTREZ:55023, HGNC:15673, MIM:612870, NM_017934, NP_060404, PHIP, WDR11, XM_005248729, XM_011535918, XM_011535919, XM_017010989, XM_017010990, XP_005248786, XP_011534220, XP_011534221, XP_016866478, XP_016866479, ndrp, pleckstrin homology domain interacting protein
Omim:OMIM:612870
Id:22eb513e-9dc2-5c73-a320-33af90875709
Hgnc:HGNC:15673
Description:PHIP subunit of CUL4-Ring ligase complex
This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients. [provided by RefSeq, Oct 2016]