GSE218378 PBX1 overexpression HCT 116 1 v 0 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE218378_PBX1 overexpression_HCT 116_1_v_0_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE218378_PBX1 overexpression_HCT 116_1_v_0_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE218378_PBX1 overexpression_HCT 116_1_v_0_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE218378_PBX1 overexpression_HCT 116_1_v_0_human_up.

Results found

Linked to

	Label	Description
	HDAC6 Gene (Entity type)	ENSG00000094631 - histone deacetylase 6
	PPP2R2C Gene (Entity type)	ENSG00000074211 - protein phosphatase 2 regulatory subunit Bgamma
	PLCG1 Gene (Entity type)	ENSG00000124181 - phospholipase C gamma 1
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	RBCK1 Gene (Entity type)	ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1
	ARF6 Gene (Entity type)	ENSG00000165527 - ARF GTPase 6
	TGFBR1 Gene (Entity type)	ENSG00000106799 - transforming growth factor beta receptor 1
	AGPAT3 Gene (Entity type)	ENSG00000160216 - 1-acylglycerol-3-phosphate O-acyltransferase 3
	SPCS3 Gene (Entity type)	ENSG00000129128 - signal peptidase complex subunit 3
	PRICKLE1 Gene (Entity type)	ENSG00000139174 - prickle planar cell polarity protein 1

HDAC6

Gene (Entity type)

ENSG00000094631 - histone deacetylase 6

PPP2R2C

Gene (Entity type)

ENSG00000074211 - protein phosphatase 2 regulatory subunit Bgamma

PLCG1

Gene (Entity type)

ENSG00000124181 - phospholipase C gamma 1

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

RBCK1

Gene (Entity type)

ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1

ARF6

Gene (Entity type)

ENSG00000165527 - ARF GTPase 6

TGFBR1

Gene (Entity type)

ENSG00000106799 - transforming growth factor beta receptor 1

AGPAT3

Gene (Entity type)

ENSG00000160216 - 1-acylglycerol-3-phosphate O-acyltransferase 3

SPCS3

Gene (Entity type)

ENSG00000129128 - signal peptidase complex subunit 3

PRICKLE1

Gene (Entity type)

ENSG00000139174 - prickle planar cell polarity protein 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.