CFTR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with CFTR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with CFTR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with CFTR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CFTR Down.

Results found

Linked to

	Label	Description
	COPB2 Gene (Entity type)	ENSG00000184432 - coat protein complex I subunit beta 2
	ATP2A1 Gene (Entity type)	ENSG00000196296 - ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
	CHRNA1 Gene (Entity type)	ENSG00000138435 - cholinergic receptor nicotinic alpha 1 subunit
	SULT1A2 Gene (Entity type)	ENSG00000197165 - sulfotransferase family 1A member 2
	TOR4A Gene (Entity type)	ENSG00000198113 - torsin family 4 member A
	ICE1 Gene (Entity type)	ENSG00000164151 - interactor of little elongation complex ELL subunit 1
	HDC Gene (Entity type)	ENSG00000140287 - histidine decarboxylase
	ADGRL3 Gene (Entity type)	ENSG00000150471 - adhesion G protein-coupled receptor L3
	CCL11 Gene (Entity type)	ENSG00000172156 - C-C motif chemokine ligand 11
	MYBPC2 Gene (Entity type)	ENSG00000086967 - myosin binding protein C2

COPB2

Gene (Entity type)

ENSG00000184432 - coat protein complex I subunit beta 2

ATP2A1

Gene (Entity type)

ENSG00000196296 - ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

CHRNA1

Gene (Entity type)

ENSG00000138435 - cholinergic receptor nicotinic alpha 1 subunit

SULT1A2

Gene (Entity type)

ENSG00000197165 - sulfotransferase family 1A member 2

TOR4A

Gene (Entity type)

ENSG00000198113 - torsin family 4 member A

ICE1

Gene (Entity type)

ENSG00000164151 - interactor of little elongation complex ELL subunit 1

HDC

Gene (Entity type)

ENSG00000140287 - histidine decarboxylase

ADGRL3

Gene (Entity type)

ENSG00000150471 - adhesion G protein-coupled receptor L3

CCL11

Gene (Entity type)

ENSG00000172156 - C-C motif chemokine ligand 11

MYBPC2

Gene (Entity type)

ENSG00000086967 - myosin binding protein C2

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CFDE Workbench

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.