ADGRL3 (Gene)

Organism:

Homo sapiens

Gene:

TARGET ID 15925

Synonyms:ADGRL3, CIRL3, CL3, ENTREZ:23284, HGNC:20974, LEC3, LPHN3, MIM:616417, NM_001322246, NM_001322402, NM_001371342, NM_001371343, NM_001371344, NM_001371345, NM_001371346, NM_001387522, NM_001387523, NM_001387524, NM_001387525, NM_001387526, NM_001387527, NM_001387528, NM_001387529, NM_001387530, NM_001387531, NM_001387532, NM_001387533, NM_001387534, NM_001387535, NM_001387536, NM_001387537, NM_001387538, NM_001387539, NM_001387540, NM_001387541, NM_001387542, NM_001387543, NM_001387544, NM_001387545, NM_001387546, NM_001387547, NM_001387548, NM_001387549, NM_001387552, NM_015236, NP_001309175, NP_001309331, NP_001358271, NP_001358272, NP_001358273, NP_001358274, NP_001358275, NP_001374451, NP_001374452, NP_001374453, NP_001374454, NP_001374455, NP_001374456, NP_001374457, NP_001374458, NP_001374459, NP_001374460, NP_001374461, NP_001374462, NP_001374463, NP_001374464, NP_001374465, NP_001374466, NP_001374467, NP_001374468, NP_001374469, NP_001374470, NP_001374471, NP_001374472, NP_001374473, NP_001374474, NP_001374475, NP_001374476, NP_001374477, NP_001374478, NP_001374481, NP_056051, XM_011531788, XM_011531791, XM_017007929, XM_017007930, XM_017007931, XM_017007932, XM_017007933, XM_017007934, XM_017007935, XM_017007936, XM_017007937, XM_017007938, XM_017007939, XM_017007940, XM_017007941, XM_017007942, XP_011530090, XP_011530093, XP_016863418, XP_016863419, XP_016863420, XP_016863421, XP_016863422, XP_016863423, XP_016863424, XP_016863425, XP_016863426, XP_016863427, XP_016863428, XP_016863429, XP_016863430, XP_016863431, adhesion G protein-coupled receptor L3

Omim:OMIM:616417

Nci:C150273

Id:ENSG00000150471

Hgnc:HGNC:20974

Entrez:23284

Ensembl:ENSG00000150471

Description:adhesion G protein-coupled receptor L3

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ADGRL3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ADGRL3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ADGRL3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ADGRL3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ADGRL3.

Results found

Linked to

	Label	Description
	GSE225869 1 V 0 TEMOZOLOMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE239844 crizotinib 6 v 9 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE229973 3 V 2 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE239844 6 V 5 CRIZOTINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE196035 GSE196037 MEN1 inhibition 5 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE162892 ISOX 3 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE238213 dopamine 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE189653,GSE203344 5 V 3 FLUOXETINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE217115 3 V 5 ALECTINIB MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS