ICOS Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with ICOS Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with ICOS Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with ICOS Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ICOS Down.

Results found

Linked to

	Label	Description
	PRKAA1 Gene (Entity type)	ENSG00000132356 - protein kinase AMP-activated catalytic subunit alpha 1
	VPS4B Gene (Entity type)	ENSG00000119541 - vacuolar protein sorting 4 homolog B
	LRRC42 Gene (Entity type)	ENSG00000116212 - leucine rich repeat containing 42
	DYNLRB1 Gene (Entity type)	ENSG00000125971 - dynein light chain roadblock-type 1
	CYP17A1 Gene (Entity type)	ENSG00000148795 - cytochrome P450 family 17 subfamily A member 1
	RAPGEF4 Gene (Entity type)	ENSG00000091428 - Rap guanine nucleotide exchange factor 4
	GNG5 Gene (Entity type)	ENSG00000174021 - G protein subunit gamma 5
	RAB8B Gene (Entity type)	ENSG00000166128 - RAB8B, member RAS oncogene family
	FEM1C Gene (Entity type)	ENSG00000145780 - fem-1 homolog C
	IER3IP1 Gene (Entity type)	ENSG00000134049 - immediate early response 3 interacting protein 1

PRKAA1

Gene (Entity type)

ENSG00000132356 - protein kinase AMP-activated catalytic subunit alpha 1

VPS4B

Gene (Entity type)

ENSG00000119541 - vacuolar protein sorting 4 homolog B

LRRC42

Gene (Entity type)

ENSG00000116212 - leucine rich repeat containing 42

DYNLRB1

Gene (Entity type)

ENSG00000125971 - dynein light chain roadblock-type 1

CYP17A1

Gene (Entity type)

ENSG00000148795 - cytochrome P450 family 17 subfamily A member 1

RAPGEF4

Gene (Entity type)

ENSG00000091428 - Rap guanine nucleotide exchange factor 4

GNG5

Gene (Entity type)

ENSG00000174021 - G protein subunit gamma 5

RAB8B

Gene (Entity type)

ENSG00000166128 - RAB8B, member RAS oncogene family

FEM1C

Gene (Entity type)

ENSG00000145780 - fem-1 homolog C

IER3IP1

Gene (Entity type)

ENSG00000134049 - immediate early response 3 interacting protein 1

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.