ICOS Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with ICOS Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with ICOS Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with ICOS Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ICOS Down.

Results found

Linked to

	Label	Description
	NRAS Gene (Entity type)	ENSG00000213281 - NRAS proto-oncogene, GTPase
	EIF4A2 Gene (Entity type)	ENSG00000156976 - eukaryotic translation initiation factor 4A2
	RAB1A Gene (Entity type)	ENSG00000138069 - RAB1A, member RAS oncogene family
	SLC35E3 Gene (Entity type)	ENSG00000175782 - solute carrier family 35 member E3
	VPS4B Gene (Entity type)	ENSG00000119541 - vacuolar protein sorting 4 homolog B
	ANKRD12 Gene (Entity type)	ENSG00000101745 - ankyrin repeat domain 12
	ABI2 Gene (Entity type)	ENSG00000138443 - abl interactor 2
	GNG5 Gene (Entity type)	ENSG00000174021 - G protein subunit gamma 5
	RAB8B Gene (Entity type)	ENSG00000166128 - RAB8B, member RAS oncogene family
	ARF1 Gene (Entity type)	ENSG00000143761 - ARF GTPase 1

NRAS

Gene (Entity type)

ENSG00000213281 - NRAS proto-oncogene, GTPase

EIF4A2

Gene (Entity type)

ENSG00000156976 - eukaryotic translation initiation factor 4A2

RAB1A

Gene (Entity type)

ENSG00000138069 - RAB1A, member RAS oncogene family

SLC35E3

Gene (Entity type)

ENSG00000175782 - solute carrier family 35 member E3

VPS4B

Gene (Entity type)

ENSG00000119541 - vacuolar protein sorting 4 homolog B

ANKRD12

Gene (Entity type)

ENSG00000101745 - ankyrin repeat domain 12

ABI2

Gene (Entity type)

ENSG00000138443 - abl interactor 2

GNG5

Gene (Entity type)

ENSG00000174021 - G protein subunit gamma 5

RAB8B

Gene (Entity type)

ENSG00000166128 - RAB8B, member RAS oncogene family

ARF1

Gene (Entity type)

ENSG00000143761 - ARF GTPase 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.