Synonyms:ABI-2, ABI2, ABI2B, AIP-1, AIP1, AblBP3, ENTREZ:10152, HGNC:24011, MIM:606442, NM_001282925, NM_001282926, NM_001282927, NM_001282932, NM_001375662, NM_001375663, NM_001375664, NM_001375665, NM_001375666, NM_001375667, NM_001375668, NM_001375669, NM_001375670, NM_001375671, NM_001375672, NM_001375673, NM_001375674, NM_001375675, NM_001375676, NM_001375677, NM_001375678, NM_001375679, NM_001375680, NM_001375681, NM_001375682, NM_001375683, NM_001375684, NM_001375685, NM_001375686, NM_001375687, NM_001375688, NM_001375689, NM_001375690, NM_001375691, NM_001375692, NM_001375693, NM_001375695, NM_001375696, NM_001375698, NM_001375699, NM_001375702, NM_001375704, NM_001375706, NM_001375707, NM_001375708, NM_001375709, NM_001375710, NM_001375711, NM_001375712, NM_001375714, NM_001375717, NM_001375719, NM_001375721, NM_001375722, NM_001375723, NM_001375724, NM_001375725, NM_001375726, NM_001375727, NM_001375728, NM_001375729, NM_001375730, NM_001375731, NM_001375732, NM_001375733, NM_001375734, NM_001375735, NM_001375736, NM_001375737, NM_001375738, NM_001375739, NM_001375740, NM_001375741, NM_001375742, NM_001375743, NM_001375744, NM_001375745, NM_001375746, NM_001375747, NM_001375748, NM_001375749, NM_001375750, NM_001375751, NM_001375752, NM_001375753, NM_001375754, NM_001375755, NM_005759, NP_001269854, NP_001269855, NP_001269856, NP_001269861, NP_001362591, NP_001362592, NP_001362593, NP_001362594, NP_001362595, NP_001362596, NP_001362597, NP_001362598, NP_001362599, NP_001362600, NP_001362601, NP_001362602, NP_001362603, NP_001362604, NP_001362605, NP_001362606, NP_001362607, NP_001362608, NP_001362609, NP_001362610, NP_001362611, NP_001362612, NP_001362613, NP_001362614, NP_001362615, NP_001362616, NP_001362617, NP_001362618, NP_001362619, NP_001362620, NP_001362621, NP_001362622, NP_001362624, NP_001362625, NP_001362627, NP_001362628, NP_001362631, NP_001362633, NP_001362635, NP_001362636, NP_001362637, NP_001362638, NP_001362639, NP_001362640, NP_001362641, NP_001362643, NP_001362646, NP_001362648, NP_001362650, NP_001362651, NP_001362652, NP_001362653, NP_001362654, NP_001362655, NP_001362656, NP_001362657, NP_001362658, NP_001362659, NP_001362660, NP_001362661, NP_001362662, NP_001362663, NP_001362664, NP_001362665, NP_001362666, NP_001362667, NP_001362668, NP_001362669, NP_001362670, NP_001362671, NP_001362672, NP_001362673, NP_001362674, NP_001362675, NP_001362676, NP_001362677, NP_001362678, NP_001362679, NP_001362680, NP_001362681, NP_001362682, NP_001362683, NP_001362684, NP_005750, NR_164704, NR_164705, NR_164706, NR_164707, NR_164708, NR_164709, NR_164710, NR_164711, NR_164712, NR_164713, NR_164714, NR_164715, NR_164716, NR_164717, NR_164718, SSH3BP2, XM_006712180, XM_006712181, XM_006712182, XM_011510473, XM_017003132, XM_017003133, XM_017003138, XM_017003143, XM_017003144, XM_024452511, XP_006712243, XP_006712244, XP_006712245, XP_011508775, XP_016858621, XP_016858622, XP_016858627, XP_016858632, XP_016858633, XP_024308279, XR_001738583, XR_001738584, abl interactor 2, argBP1, argBPIA, argBPIB
Omim:OMIM:606442
Id:ENSG00000138443
Hgnc:HGNC:24011
Description:abl interactor 2
Enables several functions, including SH3 domain binding activity; identical protein binding activity; and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction; positive regulation of cellular component organization; and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including filopodium tip; lamellipodium; and nucleoplasm. Part of SCAR complex. Is active in adherens junction. Colocalizes with actin filament. [provided by Alliance of Genome Resources, Apr 2022]
