AK2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with AK2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with AK2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with AK2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AK2 Down.

Results found

Linked to

	Label	Description
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	EGLN1 Gene (Entity type)	ENSG00000135766 - egl-9 family hypoxia inducible factor 1
	ARF6 Gene (Entity type)	ENSG00000165527 - ARF GTPase 6
	ESM1 Gene (Entity type)	ENSG00000164283 - endothelial cell specific molecule 1
	CORO2B Gene (Entity type)	ENSG00000103647 - coronin 2B
	MEX3C Gene (Entity type)	ENSG00000176624 - mex-3 RNA binding family member C
	ADGRL3 Gene (Entity type)	ENSG00000150471 - adhesion G protein-coupled receptor L3
	RGS17 Gene (Entity type)	ENSG00000091844 - regulator of G protein signaling 17
	COX17 Gene (Entity type)	ENSG00000138495 - cytochrome c oxidase copper chaperone COX17
	ADAM23 Gene (Entity type)	ENSG00000114948 - ADAM metallopeptidase domain 23

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

EGLN1

Gene (Entity type)

ENSG00000135766 - egl-9 family hypoxia inducible factor 1

ARF6

Gene (Entity type)

ENSG00000165527 - ARF GTPase 6

ESM1

Gene (Entity type)

ENSG00000164283 - endothelial cell specific molecule 1

CORO2B

Gene (Entity type)

ENSG00000103647 - coronin 2B

MEX3C

Gene (Entity type)

ENSG00000176624 - mex-3 RNA binding family member C

ADGRL3

Gene (Entity type)

ENSG00000150471 - adhesion G protein-coupled receptor L3

RGS17

Gene (Entity type)

ENSG00000091844 - regulator of G protein signaling 17

COX17

Gene (Entity type)

ENSG00000138495 - cytochrome c oxidase copper chaperone COX17

ADAM23

Gene (Entity type)

ENSG00000114948 - ADAM metallopeptidase domain 23

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.