GSE213588 trametinib NF1 9 v 1 human dn (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE213588_trametinib_NF1_9_v_1_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE213588_trametinib_NF1_9_v_1_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE213588_trametinib_NF1_9_v_1_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE213588_trametinib_NF1_9_v_1_human_dn.

Results found

Linked to

	Label	Description
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	CISH Gene (Entity type)	ENSG00000114737 - cytokine inducible SH2 containing protein
	TNFRSF14 Gene (Entity type)	ENSG00000157873 - TNF receptor superfamily member 14
	BMPR1A Gene (Entity type)	ENSG00000107779 - bone morphogenetic protein receptor type 1A
	PSEN1 Gene (Entity type)	ENSG00000080815 - presenilin 1
	USP47 Gene (Entity type)	ENSG00000170242 - ubiquitin specific peptidase 47
	ACOX1 Gene (Entity type)	ENSG00000161533 - acyl-CoA oxidase 1
	UVRAG Gene (Entity type)	ENSG00000198382 - UV radiation resistance associated
	USP32 Gene (Entity type)	ENSG00000170832 - ubiquitin specific peptidase 32
	USP25 Gene (Entity type)	ENSG00000155313 - ubiquitin specific peptidase 25

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

CISH

Gene (Entity type)

ENSG00000114737 - cytokine inducible SH2 containing protein

TNFRSF14

Gene (Entity type)

ENSG00000157873 - TNF receptor superfamily member 14

BMPR1A

Gene (Entity type)

ENSG00000107779 - bone morphogenetic protein receptor type 1A

PSEN1

Gene (Entity type)

ENSG00000080815 - presenilin 1

USP47

Gene (Entity type)

ENSG00000170242 - ubiquitin specific peptidase 47

ACOX1

Gene (Entity type)

ENSG00000161533 - acyl-CoA oxidase 1

UVRAG

Gene (Entity type)

ENSG00000198382 - UV radiation resistance associated

USP32

Gene (Entity type)

ENSG00000170832 - ubiquitin specific peptidase 32

USP25

Gene (Entity type)

ENSG00000155313 - ubiquitin specific peptidase 25

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.