LIG1 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with LIG1 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with LIG1 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with LIG1 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LIG1 Down.

Results found

Linked to

	Label	Description
	ANKLE2 Gene (Entity type)	ENSG00000176915 - ankyrin repeat and LEM domain containing 2
	PHIP Gene (Entity type)	ENSG00000146247 - PHIP subunit of CUL4-Ring ligase complex
	MARK4 Gene (Entity type)	ENSG00000007047 - microtubule affinity regulating kinase 4
	DENND4C Gene (Entity type)	ENSG00000137145 - DENN domain containing 4C
	REL Gene (Entity type)	ENSG00000162924 - REL proto-oncogene, NF-kB subunit
	VEGFD Gene (Entity type)	ENSG00000165197 - vascular endothelial growth factor D
	ARAP1 Gene (Entity type)	ENSG00000186635 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
	ZRSR2 Gene (Entity type)	ENSG00000169249 - zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
	RETREG2 Gene (Entity type)	ENSG00000144567 - reticulophagy regulator family member 2
	STX4 Gene (Entity type)	ENSG00000103496 - syntaxin 4

ANKLE2

Gene (Entity type)

ENSG00000176915 - ankyrin repeat and LEM domain containing 2

PHIP

Gene (Entity type)

ENSG00000146247 - PHIP subunit of CUL4-Ring ligase complex

MARK4

Gene (Entity type)

ENSG00000007047 - microtubule affinity regulating kinase 4

DENND4C

Gene (Entity type)

ENSG00000137145 - DENN domain containing 4C

REL

Gene (Entity type)

ENSG00000162924 - REL proto-oncogene, NF-kB subunit

VEGFD

Gene (Entity type)

ENSG00000165197 - vascular endothelial growth factor D

ARAP1

Gene (Entity type)

ENSG00000186635 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

ZRSR2

Gene (Entity type)

ENSG00000169249 - zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2

RETREG2

Gene (Entity type)

ENSG00000144567 - reticulophagy regulator family member 2

STX4

Gene (Entity type)

ENSG00000103496 - syntaxin 4

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.