CR2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with CR2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with CR2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with CR2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CR2 Down.

Results found

Linked to

	Label	Description
	TERF2 Gene (Entity type)	ENSG00000132604 - telomeric repeat binding factor 2
	ALPL Gene (Entity type)	ENSG00000162551 - alkaline phosphatase, biomineralization associated
	HPF1 Gene (Entity type)	ENSG00000056050 - histone PARylation factor 1
	CLDN5 Gene (Entity type)	ENSG00000184113 - claudin 5
	SAMM50 Gene (Entity type)	ENSG00000100347 - SAMM50 sorting and assembly machinery component
	DCAF10 Gene (Entity type)	ENSG00000122741 - DDB1 and CUL4 associated factor 10
	RER1 Gene (Entity type)	ENSG00000157916 - retention in endoplasmic reticulum sorting receptor 1
	ADCY3 Gene (Entity type)	ENSG00000138031 - adenylate cyclase 3
	CTBP1 Gene (Entity type)	ENSG00000159692 - C-terminal binding protein 1

TERF2

Gene (Entity type)

ENSG00000132604 - telomeric repeat binding factor 2

ALPL

Gene (Entity type)

ENSG00000162551 - alkaline phosphatase, biomineralization associated

HPF1

Gene (Entity type)

ENSG00000056050 - histone PARylation factor 1

CLDN5

Gene (Entity type)

ENSG00000184113 - claudin 5

SAMM50

Gene (Entity type)

ENSG00000100347 - SAMM50 sorting and assembly machinery component

DCAF10

Gene (Entity type)

ENSG00000122741 - DDB1 and CUL4 associated factor 10

RER1

Gene (Entity type)

ENSG00000157916 - retention in endoplasmic reticulum sorting receptor 1

ADCY3

Gene (Entity type)

ENSG00000138031 - adenylate cyclase 3

CTBP1

Gene (Entity type)

ENSG00000159692 - C-terminal binding protein 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.