HPF1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)

Gene:

TARGET ID 06668

Collection (Entity type)

Synonyms:C4orf27, ENTREZ:54969, HGNC:26051, HPF1, MIM:616614, NM_017867, NP_060337, histone PARylation factor 1

Id:ENSG00000056050

Entrez:54969

Ensembl:ENSG00000056050

Description:histone PARylation factor 1

Enables chromatin binding activity and histone binding activity. Involved in double-strand break repair; peptidyl-serine ADP-ribosylation; and regulation of protein modification process. Located in chromatin; nucleus; and site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HPF1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HPF1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HPF1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HPF1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HPF1.

Results found

Linked to

	Label	Description
	GSE102757 1 V 0 PANOBINOSTAT MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE153867 olaparib 6 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214596,GSE214598 1 V 0 ROSIGLITAZONE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE207499 sphingosine 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE217405 3 V 2 OSIMERTINIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE160349 IDAM T cell 2 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE171837 0 V 3 BORTEZOMIB MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE114492 GSE153671 KMT2D inhibition 12 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE164521 0 V 1 NITRIC OXIDE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE216043 cisplatin 3 v 9 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE102757 1 V 0 PANOBINOSTAT MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE153867 olaparib 6 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214596,GSE214598 1 V 0 ROSIGLITAZONE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE207499 sphingosine 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE217405 3 V 2 OSIMERTINIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE160349 IDAM T cell 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE171837 0 V 3 BORTEZOMIB MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE114492 GSE153671 KMT2D inhibition 12 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE164521 0 V 1 NITRIC OXIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE216043 cisplatin 3 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.