NPEPPS Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with NPEPPS Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with NPEPPS Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with NPEPPS Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NPEPPS Down.

Results found

Linked to

	Label	Description
	HCK Gene (Entity type)	ENSG00000101336 - HCK proto-oncogene, Src family tyrosine kinase
	APOBEC3A Gene (Entity type)	ENSG00000128383 - apolipoprotein B mRNA editing enzyme catalytic subunit 3A
	JAK2 Gene (Entity type)	ENSG00000096968 - Janus kinase 2
	VWA8 Gene (Entity type)	ENSG00000102763 - von Willebrand factor A domain containing 8
	RAB8B Gene (Entity type)	ENSG00000166128 - RAB8B, member RAS oncogene family
	OSTF1 Gene (Entity type)	ENSG00000134996 - osteoclast stimulating factor 1
	BACH1 Gene (Entity type)	ENSG00000156273 - BTB domain and CNC homolog 1
	ADPRM Gene (Entity type)	ENSG00000170222 - ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
	DNAJA2 Gene (Entity type)	ENSG00000069345 - DnaJ heat shock protein family (Hsp40) member A2
	HOXA1 Gene (Entity type)	ENSG00000105991 - homeobox A1

HCK

Gene (Entity type)

ENSG00000101336 - HCK proto-oncogene, Src family tyrosine kinase

APOBEC3A

Gene (Entity type)

ENSG00000128383 - apolipoprotein B mRNA editing enzyme catalytic subunit 3A

JAK2

Gene (Entity type)

ENSG00000096968 - Janus kinase 2

VWA8

Gene (Entity type)

ENSG00000102763 - von Willebrand factor A domain containing 8

RAB8B

Gene (Entity type)

ENSG00000166128 - RAB8B, member RAS oncogene family

OSTF1

Gene (Entity type)

ENSG00000134996 - osteoclast stimulating factor 1

BACH1

Gene (Entity type)

ENSG00000156273 - BTB domain and CNC homolog 1

ADPRM

Gene (Entity type)

ENSG00000170222 - ADP-ribose/CDP-alcohol diphosphatase, manganese dependent

DNAJA2

Gene (Entity type)

ENSG00000069345 - DnaJ heat shock protein family (Hsp40) member A2

HOXA1

Gene (Entity type)

ENSG00000105991 - homeobox A1

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.