NPPB Down (Gene Set)

Dcc Asset:

LINCS L1000 Chem Pert Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with NPPB Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with NPPB Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with NPPB Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NPPB Down.

Results found

Linked to

	Label	Description
	POMC Gene (Entity type)	ENSG00000115138 - proopiomelanocortin
	SLC35A3 Gene (Entity type)	ENSG00000117620 - solute carrier family 35 member A3
	CHIT1 Gene (Entity type)	ENSG00000133063 - chitinase 1
	TNFRSF25 Gene (Entity type)	ENSG00000215788 - TNF receptor superfamily member 25
	REL Gene (Entity type)	ENSG00000162924 - REL proto-oncogene, NF-kB subunit
	HPS5 Gene (Entity type)	ENSG00000110756 - HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
	GPD1 Gene (Entity type)	ENSG00000167588 - glycerol-3-phosphate dehydrogenase 1
	NCF4 Gene (Entity type)	ENSG00000100365 - neutrophil cytosolic factor 4
	CMPK1 Gene (Entity type)	ENSG00000162368 - cytidine/uridine monophosphate kinase 1
	ABCC6 Gene (Entity type)	ENSG00000091262 - ATP binding cassette subfamily C member 6

POMC

Gene (Entity type)

ENSG00000115138 - proopiomelanocortin

SLC35A3

Gene (Entity type)

ENSG00000117620 - solute carrier family 35 member A3

CHIT1

Gene (Entity type)

ENSG00000133063 - chitinase 1

TNFRSF25

Gene (Entity type)

ENSG00000215788 - TNF receptor superfamily member 25

REL

Gene (Entity type)

ENSG00000162924 - REL proto-oncogene, NF-kB subunit

HPS5

Gene (Entity type)

ENSG00000110756 - HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

GPD1

Gene (Entity type)

ENSG00000167588 - glycerol-3-phosphate dehydrogenase 1

NCF4

Gene (Entity type)

ENSG00000100365 - neutrophil cytosolic factor 4

CMPK1

Gene (Entity type)

ENSG00000162368 - cytidine/uridine monophosphate kinase 1

ABCC6

Gene (Entity type)

ENSG00000091262 - ATP binding cassette subfamily C member 6

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.