TPRKB Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with TPRKB Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with TPRKB Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with TPRKB Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TPRKB Up.

Results found

Linked to

	Label	Description
	MAD1L1 Gene (Entity type)	ENSG00000002822 - mitotic arrest deficient 1 like 1
	CYP7A1 Gene (Entity type)	ENSG00000167910 - cytochrome P450 family 7 subfamily A member 1
	HPD Gene (Entity type)	ENSG00000158104 - 4-hydroxyphenylpyruvate dioxygenase
	ADAM8 Gene (Entity type)	ENSG00000151651 - ADAM metallopeptidase domain 8
	NSUN5 Gene (Entity type)	ENSG00000130305 - NOP2/Sun RNA methyltransferase 5
	IVL Gene (Entity type)	ENSG00000163207 - involucrin
	CHD1 Gene (Entity type)	ENSG00000153922 - chromodomain helicase DNA binding protein 1
	RNF44 Gene (Entity type)	ENSG00000146083 - ring finger protein 44
	WAPL Gene (Entity type)	ENSG00000062650 - WAPL cohesin release factor
	ABCC2 Gene (Entity type)	ENSG00000023839 - ATP binding cassette subfamily C member 2

MAD1L1

Gene (Entity type)

ENSG00000002822 - mitotic arrest deficient 1 like 1

CYP7A1

Gene (Entity type)

ENSG00000167910 - cytochrome P450 family 7 subfamily A member 1

HPD

Gene (Entity type)

ENSG00000158104 - 4-hydroxyphenylpyruvate dioxygenase

ADAM8

Gene (Entity type)

ENSG00000151651 - ADAM metallopeptidase domain 8

NSUN5

Gene (Entity type)

ENSG00000130305 - NOP2/Sun RNA methyltransferase 5

IVL

Gene (Entity type)

ENSG00000163207 - involucrin

CHD1

Gene (Entity type)

ENSG00000153922 - chromodomain helicase DNA binding protein 1

RNF44

Gene (Entity type)

ENSG00000146083 - ring finger protein 44

WAPL

Gene (Entity type)

ENSG00000062650 - WAPL cohesin release factor

ABCC2

Gene (Entity type)

ENSG00000023839 - ATP binding cassette subfamily C member 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.