PLTP Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PLTP Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PLTP Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PLTP Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLTP Up.

Results found

Linked to

	Label	Description
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	EIF4E Gene (Entity type)	ENSG00000151247 - eukaryotic translation initiation factor 4E
	ATMIN Gene (Entity type)	ENSG00000166454 - ATM interactor
	SLC22A3 Gene (Entity type)	ENSG00000146477 - solute carrier family 22 member 3
	CA3 Gene (Entity type)	ENSG00000164879 - carbonic anhydrase 3
	MACROD1 Gene (Entity type)	ENSG00000133315 - mono-ADP ribosylhydrolase 1
	RASIP1 Gene (Entity type)	ENSG00000105538 - Ras interacting protein 1
	SPCS3 Gene (Entity type)	ENSG00000129128 - signal peptidase complex subunit 3
	PHIP Gene (Entity type)	ENSG00000146247 - PHIP subunit of CUL4-Ring ligase complex
	EXOSC8 Gene (Entity type)	ENSG00000120699 - exosome component 8

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

EIF4E

Gene (Entity type)

ENSG00000151247 - eukaryotic translation initiation factor 4E

ATMIN

Gene (Entity type)

ENSG00000166454 - ATM interactor

SLC22A3

Gene (Entity type)

ENSG00000146477 - solute carrier family 22 member 3

CA3

Gene (Entity type)

ENSG00000164879 - carbonic anhydrase 3

MACROD1

Gene (Entity type)

ENSG00000133315 - mono-ADP ribosylhydrolase 1

RASIP1

Gene (Entity type)

ENSG00000105538 - Ras interacting protein 1

SPCS3

Gene (Entity type)

ENSG00000129128 - signal peptidase complex subunit 3

PHIP

Gene (Entity type)

ENSG00000146247 - PHIP subunit of CUL4-Ring ligase complex

EXOSC8

Gene (Entity type)

ENSG00000120699 - exosome component 8

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.