TLK1 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with TLK1 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with TLK1 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with TLK1 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TLK1 Up.

Results found

Linked to

	Label	Description
	VAMP7 Gene (Entity type)	ENSG00000292366 - vesicle associated membrane protein 7
	GTF2H3 Gene (Entity type)	ENSG00000111358 - general transcription factor IIH subunit 3
	RGS20 Gene (Entity type)	ENSG00000147509 - regulator of G protein signaling 20
	DCAF7 Gene (Entity type)	ENSG00000136485 - DDB1 and CUL4 associated factor 7
	RAPGEFL1 Gene (Entity type)	ENSG00000108352 - Rap guanine nucleotide exchange factor like 1
	PPP2CB Gene (Entity type)	ENSG00000104695 - protein phosphatase 2 catalytic subunit beta
	LIN28A Gene (Entity type)	ENSG00000131914 - lin-28 RNA binding posttranscriptional regulator A
	VAMP7 Gene (Entity type)	ENSG00000124333 - vesicle associated membrane protein 7
	HOXB13 Gene (Entity type)	ENSG00000159184 - homeobox B13
	MAP4K3 Gene (Entity type)	ENSG00000011566 - mitogen-activated protein kinase kinase kinase kinase 3

VAMP7

Gene (Entity type)

ENSG00000292366 - vesicle associated membrane protein 7

GTF2H3

Gene (Entity type)

ENSG00000111358 - general transcription factor IIH subunit 3

RGS20

Gene (Entity type)

ENSG00000147509 - regulator of G protein signaling 20

DCAF7

Gene (Entity type)

ENSG00000136485 - DDB1 and CUL4 associated factor 7

RAPGEFL1

Gene (Entity type)

ENSG00000108352 - Rap guanine nucleotide exchange factor like 1

PPP2CB

Gene (Entity type)

ENSG00000104695 - protein phosphatase 2 catalytic subunit beta

LIN28A

Gene (Entity type)

ENSG00000131914 - lin-28 RNA binding posttranscriptional regulator A

VAMP7

Gene (Entity type)

ENSG00000124333 - vesicle associated membrane protein 7

HOXB13

Gene (Entity type)

ENSG00000159184 - homeobox B13

MAP4K3

Gene (Entity type)

ENSG00000011566 - mitogen-activated protein kinase kinase kinase kinase 3

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.