Synonyms:ENTREZ:8601, HGNC:14600, MIM:607193, NM_001286673, NM_001286674, NM_001286675, NM_003702, NM_170587, NP_001273602, NP_001273603, NP_001273604, NP_003693, NP_733466, NR_104578, NR_104579, RGS20, RGSZ1, ZGAP1, g(z)GAP, gz-GAP, regulator of G protein signaling 20
Omim:OMIM:607193
Id:6105adad-6355-528e-8fdd-7269aee58a63
Hgnc:HGNC:14600
Description:regulator of G protein signaling 20
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]