SIGIRR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SIGIRR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SIGIRR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SIGIRR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIGIRR Down.

Results found

Linked to

	Label	Description
	SNRK Gene (Entity type)	ENSG00000163788 - SNF related kinase
	GSS Gene (Entity type)	ENSG00000100983 - glutathione synthetase
	ADAM8 Gene (Entity type)	ENSG00000151651 - ADAM metallopeptidase domain 8
	PRRC1 Gene (Entity type)	ENSG00000164244 - proline rich coiled-coil 1
	ZNF430 Gene (Entity type)	ENSG00000118620 - zinc finger protein 430
	PREPL Gene (Entity type)	ENSG00000138078 - prolyl endopeptidase like
	SHOC2 Gene (Entity type)	ENSG00000108061 - SHOC2 leucine rich repeat scaffold protein
	PAQR6 Gene (Entity type)	ENSG00000160781 - progestin and adipoQ receptor family member 6
	STK17B Gene (Entity type)	ENSG00000081320 - serine/threonine kinase 17b
	PCBP4 Gene (Entity type)	ENSG00000090097 - poly(rC) binding protein 4

SNRK

Gene (Entity type)

ENSG00000163788 - SNF related kinase

GSS

Gene (Entity type)

ENSG00000100983 - glutathione synthetase

ADAM8

Gene (Entity type)

ENSG00000151651 - ADAM metallopeptidase domain 8

PRRC1

Gene (Entity type)

ENSG00000164244 - proline rich coiled-coil 1

ZNF430

Gene (Entity type)

ENSG00000118620 - zinc finger protein 430

PREPL

Gene (Entity type)

ENSG00000138078 - prolyl endopeptidase like

SHOC2

Gene (Entity type)

ENSG00000108061 - SHOC2 leucine rich repeat scaffold protein

PAQR6

Gene (Entity type)

ENSG00000160781 - progestin and adipoQ receptor family member 6

STK17B

Gene (Entity type)

ENSG00000081320 - serine/threonine kinase 17b

PCBP4

Gene (Entity type)

ENSG00000090097 - poly(rC) binding protein 4

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.