SIRT3 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SIRT3 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SIRT3 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SIRT3 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIRT3 Up.

Results found

Linked to

	Label	Description
	C4BPB Gene (Entity type)	ENSG00000123843 - complement component 4 binding protein beta
	CHIT1 Gene (Entity type)	ENSG00000133063 - chitinase 1
	GRIA1 Gene (Entity type)	ENSG00000155511 - glutamate ionotropic receptor AMPA type subunit 1
	CAMK2G Gene (Entity type)	ENSG00000148660 - calcium/calmodulin dependent protein kinase II gamma
	DOP1B Gene (Entity type)	ENSG00000142197 - DOP1 leucine zipper like protein B
	MDH1 Gene (Entity type)	ENSG00000014641 - malate dehydrogenase 1
	HSD3B2 Gene (Entity type)	ENSG00000203859 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
	HIGD2A Gene (Entity type)	ENSG00000146066 - HIG1 hypoxia inducible domain family member 2A
	TERT Gene (Entity type)	ENSG00000164362 - telomerase reverse transcriptase
	COLGALT2 Gene (Entity type)	ENSG00000198756 - collagen beta(1-O)galactosyltransferase 2

C4BPB

Gene (Entity type)

ENSG00000123843 - complement component 4 binding protein beta

CHIT1

Gene (Entity type)

ENSG00000133063 - chitinase 1

GRIA1

Gene (Entity type)

ENSG00000155511 - glutamate ionotropic receptor AMPA type subunit 1

CAMK2G

Gene (Entity type)

ENSG00000148660 - calcium/calmodulin dependent protein kinase II gamma

DOP1B

Gene (Entity type)

ENSG00000142197 - DOP1 leucine zipper like protein B

MDH1

Gene (Entity type)

ENSG00000014641 - malate dehydrogenase 1

HSD3B2

Gene (Entity type)

ENSG00000203859 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

HIGD2A

Gene (Entity type)

ENSG00000146066 - HIG1 hypoxia inducible domain family member 2A

TERT

Gene (Entity type)

ENSG00000164362 - telomerase reverse transcriptase

COLGALT2

Gene (Entity type)

ENSG00000198756 - collagen beta(1-O)galactosyltransferase 2

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.