DHFR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with DHFR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with DHFR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with DHFR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DHFR Down.

Results found

Linked to

	Label	Description
	UQCRC1 Gene (Entity type)	ENSG00000010256 - ubiquinol-cytochrome c reductase core protein 1
	C4BPB Gene (Entity type)	ENSG00000123843 - complement component 4 binding protein beta
	PNOC Gene (Entity type)	ENSG00000168081 - prepronociceptin
	APOBEC3A Gene (Entity type)	ENSG00000128383 - apolipoprotein B mRNA editing enzyme catalytic subunit 3A
	NAPA Gene (Entity type)	ENSG00000105402 - NSF attachment protein alpha
	POLR2E Gene (Entity type)	ENSG00000099817 - RNA polymerase II, I and III subunit E
	UGT2A3 Gene (Entity type)	ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3
	ADAM23 Gene (Entity type)	ENSG00000114948 - ADAM metallopeptidase domain 23
	SV2B Gene (Entity type)	ENSG00000185518 - synaptic vesicle glycoprotein 2B
	ATP2B2 Gene (Entity type)	ENSG00000157087 - ATPase plasma membrane Ca2+ transporting 2

UQCRC1

Gene (Entity type)

ENSG00000010256 - ubiquinol-cytochrome c reductase core protein 1

C4BPB

Gene (Entity type)

ENSG00000123843 - complement component 4 binding protein beta

PNOC

Gene (Entity type)

ENSG00000168081 - prepronociceptin

APOBEC3A

Gene (Entity type)

ENSG00000128383 - apolipoprotein B mRNA editing enzyme catalytic subunit 3A

NAPA

Gene (Entity type)

ENSG00000105402 - NSF attachment protein alpha

POLR2E

Gene (Entity type)

ENSG00000099817 - RNA polymerase II, I and III subunit E

UGT2A3

Gene (Entity type)

ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3

ADAM23

Gene (Entity type)

ENSG00000114948 - ADAM metallopeptidase domain 23

SV2B

Gene (Entity type)

ENSG00000185518 - synaptic vesicle glycoprotein 2B

ATP2B2

Gene (Entity type)

ENSG00000157087 - ATPase plasma membrane Ca2+ transporting 2

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.