PTENP1 (Gene)

Entrez:11191

Description:phosphatase and tensin homolog pseudogene 1

PTENP1 represents a highly homologous processed pseudogene of PTEN (phosphatase and tensin homolog), a protein that encodes a tumor suppressor that functions by negatively regulating the AKT/PKB signaling pathway. PTENP1 is found on chromosome 9 and regulates PTEN by both sense and antisense RNAs (Gene ID: 101243555). This long-noncoding RNA (lncRNA) acts as a decoy for PTEN targeting microRNAs and also exerts a tumor suppressive activity. [provided by RefSeq, Jun 2020]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PTENP1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PTENP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PTENP1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PTENP1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PTENP1.

Results found

Linked to

	Label	Description
	GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 0 v 9 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE104526 p53 LSD1 inhibition 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE218378 PBX1 overexpression HCT 116 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE236502 paclitaxel 2 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE195568 palbociclib 2 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE224004 GSE224005 CHD4 EWS-FLI1 knockdown 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE229973 cisplatin 4 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 lenalidomide 0 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 IKZF1 CRBN MEIS2 IKZF3 inhibition Lenalidomide 0 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE214931 temozolomide 2 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 0 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE104526 p53 LSD1 inhibition 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE218378 PBX1 overexpression HCT 116 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE236502 paclitaxel 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE195568 palbociclib 2 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE224004 GSE224005 CHD4 EWS-FLI1 knockdown 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE229973 cisplatin 4 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 lenalidomide 0 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 IKZF1 CRBN MEIS2 IKZF3 inhibition Lenalidomide 0 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE214931 temozolomide 2 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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