LRRC53 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:105378803, HGNC:25255, LRRC53, NM_001364666, NM_001382280, NP_001351595, NP_001369209, XM_011542512, XM_017003081, XP_011540814, XP_016858570, leucine rich repeat containing 53

Id:ENSG00000162621

Hgnc:HGNC:25255

Entrez:105378803

Ensembl:ENSG00000162621

Description:leucine rich repeat containing 53

Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LRRC53's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LRRC53.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LRRC53.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LRRC53.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LRRC53.

Results found

Linked to

	Label	Description
	GSE108464 AZ-628 11 v 12 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 0 v 9 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE213845 EZH2 inhibition 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE213845 EZH2 inhibition 4 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 10 v 6 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE139261 PDX SOX10 overexpression G144 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE169152 3 V 1 IBRUTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE130401 trametinib YAP 6 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE113369 p53 inhibition 2 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE108464 AZ-628 11 v 12 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 0 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE213845 EZH2 inhibition 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE213845 EZH2 inhibition 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 10 v 6 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE139261 PDX SOX10 overexpression G144 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE169152 3 V 1 IBRUTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE130401 trametinib YAP 6 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE113369 p53 inhibition 2 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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