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HERC1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:8925, HECT and RLD domain containing E3 ubiquitin protein ligase family member 1, HERC1, HGNC:4867, MDFPMR, MIM:605109, NM_003922, NP_003913, XM_017022699, XM_017022700, XM_017022701, XM_017022702, XM_017022703, XM_017022704, XM_017022705, XM_017022706, XP_016878188, XP_016878189, XP_016878190, XP_016878191, XP_016878192, XP_016878193, XP_016878194, XP_016878195, p532, p619
Omim:OMIM:605109
Id:ENSG00000103657
Hgnc:HGNC:4867
Entrez:8925
Ensembl:ENSG00000103657
Description:HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HERC1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HERC1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HERC1.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HERC1.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HERC1.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE186471 1 V 2 CARNOSOL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE212231 GSE218491 SHP2 inhibition 3 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE57871 GLI1 PSMD13 knockdown HCT 116 Vorinostat 11 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE57871 vorinostat HCT 116 11 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193993 SSTR2 knockout 5 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE158834 ADIPOR2 knockout HEK293 12 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE217552 fisetin 3 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE80098 GSE80366 progesterone 0 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE171177,GSE171181 1 V 0 E7107 HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE189859 GSE189861 IDH1 knockout 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE186471 1 V 2 CARNOSOL HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE212231 GSE218491 SHP2 inhibition 3 v 5 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE57871 GLI1 PSMD13 knockdown HCT 116 Vorinostat 11 v 10 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE57871 vorinostat HCT 116 11 v 10 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 5 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE158834 ADIPOR2 knockout HEK293 12 v 5 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE217552 fisetin 3 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE80098 GSE80366 progesterone 0 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE171177,GSE171181 1 V 0 E7107 HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE189859 GSE189861 IDH1 knockout 4 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.