GSE212231 GSE218491 SHP2 inhibition 3 v 5 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE212231_GSE218491_SHP2 inhibition_3_v_5_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE212231_GSE218491_SHP2 inhibition_3_v_5_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE212231_GSE218491_SHP2 inhibition_3_v_5_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE212231_GSE218491_SHP2 inhibition_3_v_5_human_up.

Results found

Linked to

	Label	Description
	BRAF Gene (Entity type)	ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	S1PR3 Gene (Entity type)	ENSG00000213694 - sphingosine-1-phosphate receptor 3
	ERN1 Gene (Entity type)	ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1
	BAZ1B Gene (Entity type)	ENSG00000009954 - bromodomain adjacent to zinc finger domain 1B
	CHAF1B Gene (Entity type)	ENSG00000159259 - chromatin assembly factor 1 subunit B
	HIPK1 Gene (Entity type)	ENSG00000163349 - homeodomain interacting protein kinase 1
	SEC16A Gene (Entity type)	ENSG00000148396 - SEC16 homolog A, endoplasmic reticulum export factor
	MANBA Gene (Entity type)	ENSG00000109323 - mannosidase beta

BRAF

Gene (Entity type)

ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

S1PR3

Gene (Entity type)

ENSG00000213694 - sphingosine-1-phosphate receptor 3

ERN1

Gene (Entity type)

ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1

BAZ1B

Gene (Entity type)

ENSG00000009954 - bromodomain adjacent to zinc finger domain 1B

CHAF1B

Gene (Entity type)

ENSG00000159259 - chromatin assembly factor 1 subunit B

HIPK1

Gene (Entity type)

ENSG00000163349 - homeodomain interacting protein kinase 1

SEC16A

Gene (Entity type)

ENSG00000148396 - SEC16 homolog A, endoplasmic reticulum export factor

MANBA

Gene (Entity type)

ENSG00000109323 - mannosidase beta

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.