RAE1 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:8480, Gle2, HGNC:9828, MIG14, MIM:603343, MRNP41, Mnrp41, NM_001015885, NM_003610, NP_001015885, NP_003601, RAE1, XM_005260582, XM_005260583, XM_011529087, XM_011529088, XM_011529089, XM_017028108, XP_005260639, XP_005260640, XP_011527389, XP_011527390, XP_011527391, XP_016883597, dJ481F12.3, dJ800J21.1, ribonucleic acid export 1

Omim:OMIM:603343

Id:ENSG00000101146

Hgnc:HGNC:9828

Entrez:8480

Ensembl:ENSG00000101146

Description:ribonucleic acid export 1

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View RAE1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with RAE1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using RAE1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for RAE1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RAE1.

Results found

Linked to

	Label	Description
	GSE218773 ABL2 knockdown Hep-G2 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE102757 1 V 0 PANOBINOSTAT MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE188728 GSE188730 BRG1 HSA BCL7 knockdown B cell 3 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE125782 3 V 1 GLUTAMINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE77108 saha 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE153871 cytarabine U2OS 5 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE77108 saha 6 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 trametinib NF1 9 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680 GSE182683 dexamethasone 5 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE216540 fulvestrant 10 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE218773 ABL2 knockdown Hep-G2 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE102757 1 V 0 PANOBINOSTAT MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE188728 GSE188730 BRG1 HSA BCL7 knockdown B cell 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE125782 3 V 1 GLUTAMINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE77108 saha 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE153871 cytarabine U2OS 5 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE77108 saha 6 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 trametinib NF1 9 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680 GSE182683 dexamethasone 5 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE216540 fulvestrant 10 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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