GSE213588 trametinib NF1 9 v 11 human dn (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE213588_trametinib_NF1_9_v_11_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE213588_trametinib_NF1_9_v_11_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE213588_trametinib_NF1_9_v_11_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE213588_trametinib_NF1_9_v_11_human_dn.

Results found

Linked to

	Label	Description
	PFDN2 Gene (Entity type)	ENSG00000143256 - prefoldin subunit 2
	DFFA Gene (Entity type)	ENSG00000160049 - DNA fragmentation factor subunit alpha
	POLR3K Gene (Entity type)	ENSG00000161980 - RNA polymerase III subunit K
	ADCY3 Gene (Entity type)	ENSG00000138031 - adenylate cyclase 3
	POLA2 Gene (Entity type)	ENSG00000014138 - DNA polymerase alpha 2, accessory subunit
	BAZ1B Gene (Entity type)	ENSG00000009954 - bromodomain adjacent to zinc finger domain 1B
	CHAF1B Gene (Entity type)	ENSG00000159259 - chromatin assembly factor 1 subunit B
	PRPS1 Gene (Entity type)	ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1
	PLK4 Gene (Entity type)	ENSG00000142731 - polo like kinase 4
	SNRPA1 Gene (Entity type)	ENSG00000131876 - small nuclear ribonucleoprotein polypeptide A'

PFDN2

Gene (Entity type)

ENSG00000143256 - prefoldin subunit 2

DFFA

Gene (Entity type)

ENSG00000160049 - DNA fragmentation factor subunit alpha

POLR3K

Gene (Entity type)

ENSG00000161980 - RNA polymerase III subunit K

ADCY3

Gene (Entity type)

ENSG00000138031 - adenylate cyclase 3

POLA2

Gene (Entity type)

ENSG00000014138 - DNA polymerase alpha 2, accessory subunit

BAZ1B

Gene (Entity type)

ENSG00000009954 - bromodomain adjacent to zinc finger domain 1B

CHAF1B

Gene (Entity type)

ENSG00000159259 - chromatin assembly factor 1 subunit B

PRPS1

Gene (Entity type)

ENSG00000147224 - phosphoribosyl pyrophosphate synthetase 1

PLK4

Gene (Entity type)

ENSG00000142731 - polo like kinase 4

SNRPA1

Gene (Entity type)

ENSG00000131876 - small nuclear ribonucleoprotein polypeptide A'

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.