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CYLD (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:BRSS, CDMT, CYLD lysine 63 deubiquitinase, CYLD, CYLD1, CYLDI, EAC, ENTREZ:1540, FTDALS8, HGNC:2584, MFT, MFT1, MIM:605018, NM_001042355, NM_001042412, NM_001378743, NM_001378744, NM_001378745, NM_001378746, NM_001378747, NM_001378748, NM_001378749, NM_001378750, NM_001378751, NM_001378752, NM_001378753, NM_001378754, NM_001378755, NM_015247, NP_001035814, NP_001035877, NP_001365672, NP_001365673, NP_001365674, NP_001365675, NP_001365676, NP_001365677, NP_001365678, NP_001365679, NP_001365680, NP_001365681, NP_001365682, NP_001365683, NP_001365684, NP_056062, NR_166071, SBS, TEM, USPL2, XM_011522911, XM_017022978, XM_017022980, XP_011521213, XP_016878467, XP_016878469, XR_933218
Omim:OMIM:605018
Id:ENSG00000083799
Hgnc:HGNC:2584
Entrez:1540
Ensembl:ENSG00000083799
Description:CYLD lysine 63 deubiquitinase
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CYLD's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CYLD.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CYLD.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CYLD.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CYLD.

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.