SCGE:18000000092 (Project)

Dcc Asset:

scge cfde submission 20251016 143304.zip

Processed File (Entity type)

Dcc:

SCGE

DCC (Entity type)

Child Project:

SCGE:1020

Project (Entity type)

Persistent Id:https://scge.mcw.edu/toolkit/data/experiments/experiment/18000000092

Description:Human kidney organoids generated from human ES and iPS cells are used to evaluate tropism of AAV2, AAV8, and AAV9 that express eGFP under CMV promoter. Organoids are exposed to AAVs at MOI 10^5 from differentiaiton day 21 to 28. Immunohistochemistry is performed to visualize transduced cells with staining for podocytes (PODXL), proximal tubules (LTL), loops of Henle and distal nephrons (CDH1), interstitial stromal cells (PDGFRb), and endothelia (CD31). AAV2/2 shows the highest transduction efficiency among three serotypes evaluated, and the GFP expression is highest in proximal tubular cells.

Abbreviation:SCGE18000000092

Results found

Linked to

	Label	Description
	SCGE:15000003399 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000092 project
	SCGE:15000003402 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000092 project
	SCGE:15000003400 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000092 project
	SCGE:1020 Project (Entity type)	SCGE study 1020
	SCGE:15000003401 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000092 project

SCGE:15000003399

Biosample (Entity type)

A biosample from SCGE produced as part of the SCGE:18000000092 project

SCGE:15000003402

Biosample (Entity type)

A biosample from SCGE produced as part of the SCGE:18000000092 project

SCGE:15000003400

Biosample (Entity type)

A biosample from SCGE produced as part of the SCGE:18000000092 project

SCGE:1020

Project (Entity type)

SCGE study 1020

SCGE:15000003401

Biosample (Entity type)

A biosample from SCGE produced as part of the SCGE:18000000092 project

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CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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