SCGE (DCC)

Info Url:https://cfde.cloud/info/dcc/SCGE

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Homepage:https://scge.mcw.edu/

Description:The NIH Common Fund’s Somatic Cell Genome Editing (SCGE) program aims to reduce the burden of diseases caused by genetic changes. Genome editing technologies present an exciting prospect for treatments and possibly even cure for these diseases. During its first 5-year phase (FY18-FY23), SCGE developed quality tools to perform and assess effective genome editing tools in non-reproductive (“somatic”) cells of the body. In its second phase (FY23-27), SCGE will accelerate the translation of genome editing therapies into the clinic.

Primary Project:

SCGE:1

Project (Entity type)

Results found

Linked to

	Label	Description
	scge cfde submission 20251016 143304.zip Processed File (Entity type)	A contributed C2M2
	SCGE:13000000041 Subject (Entity type)	A subject from SCGE produced as part of the SCGE:1 project
	SCGE:18000000087 Project (Entity type)	Ten AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and c...
	SCGE:13000000023 Subject (Entity type)	A subject from SCGE produced as part of the SCGE:1 project
	SCGE:13000000031 Subject (Entity type)	A subject from SCGE produced as part of the SCGE:1 project
	SCGE:18000000005 Project (Entity type)	Delivery of Cas9 RNP targeting human CFTR in Primary human epithelia cells. Gene editing efficiency ...
	SCGE:13000000036 Subject (Entity type)	A subject from SCGE produced as part of the SCGE:1 project
	SCGE:18000000006 Project (Entity type)	Delivery of Cas12a RNP targeting human CFTR in Primary human epithelia cells. Gene editing efficienc...
	SCGE:13000000021 Subject (Entity type)	A subject from SCGE produced as part of the SCGE:1 project
	SCGE:18000000013 Project (Entity type)	110 guide RNAs and SpCas9 were transfected into human T-cells. Indel rates were measured by targete...

scge cfde submission 20251016 143304.zip

Processed File (Entity type)

A contributed C2M2

SCGE:13000000041

Subject (Entity type)