SCGE:18000000034 (Project)

Dcc Asset:

scge cfde submission 20251016 143304.zip

Processed File (Entity type)

Dcc:

SCGE

DCC (Entity type)

Child Project:

SCGE:1056

Project (Entity type)

Persistent Id:https://scge.mcw.edu/toolkit/data/experiments/experiment/18000000034

Description:A dual vector strategy was employed: one delivering a single guide RNA and CB driven SaCas9, and another delivering the second guide RNA and CB driven SaCas9. This strategy was evaluted with both AAV9 (n=4) and AAVcc47 (n=5) by intravenous injection in Ai9 mice. A total dose of 2e12vg was injected into each mouse (1e12vg each vector mixed 1:1) and organs were harvested 4 weeks post injection. Editing efficency was determined by calculating percent TdTomato+ cells normalized to Dapi+ cells in liver and heart.

Abbreviation:SCGE18000000034

Results found

Linked to

	Label	Description
	SCGE:1056 Project (Entity type)	SCGE study 1056
	SCGE:15000001006 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001007 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001012 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001010 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001005 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001009 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001014 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001008 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project
	SCGE:15000001011 Biosample (Entity type)	A biosample from SCGE produced as part of the SCGE:18000000034 project

SCGE:1056

Project (Entity type)

SCGE study 1056

SCGE:15000001006

Biosample (Entity type)