LYAR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with LYAR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with LYAR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with LYAR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LYAR Down.

Results found

Linked to

	Label	Description
	PPP2R5C Gene (Entity type)	ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma
	SIGIRR Gene (Entity type)	ENSG00000185187 - single Ig and TIR domain containing
	PRELID3B Gene (Entity type)	ENSG00000101166 - PRELI domain containing 3B
	IL11RA Gene (Entity type)	ENSG00000137070 - interleukin 11 receptor subunit alpha
	HSD17B8 Gene (Entity type)	ENSG00000204228 - hydroxysteroid 17-beta dehydrogenase 8
	EVA1B Gene (Entity type)	ENSG00000142694 - eva-1 homolog B
	MEP1A Gene (Entity type)	ENSG00000112818 - meprin A subunit alpha
	SLURP1 Gene (Entity type)	ENSG00000126233 - secreted LY6/PLAUR domain containing 1
	STK3 Gene (Entity type)	ENSG00000104375 - serine/threonine kinase 3
	HACL2 Gene (Entity type)	ENSG00000105135 - 2-hydroxyacyl-CoA lyase 2

PPP2R5C

Gene (Entity type)

ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

SIGIRR

Gene (Entity type)

ENSG00000185187 - single Ig and TIR domain containing

PRELID3B

Gene (Entity type)

ENSG00000101166 - PRELI domain containing 3B

IL11RA

Gene (Entity type)

ENSG00000137070 - interleukin 11 receptor subunit alpha

HSD17B8

Gene (Entity type)

ENSG00000204228 - hydroxysteroid 17-beta dehydrogenase 8

EVA1B

Gene (Entity type)

ENSG00000142694 - eva-1 homolog B

MEP1A

Gene (Entity type)

ENSG00000112818 - meprin A subunit alpha

SLURP1

Gene (Entity type)

ENSG00000126233 - secreted LY6/PLAUR domain containing 1

STK3

Gene (Entity type)

ENSG00000104375 - serine/threonine kinase 3

HACL2

Gene (Entity type)

ENSG00000105135 - 2-hydroxyacyl-CoA lyase 2

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.