TNC Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with TNC Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with TNC Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with TNC Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TNC Down.

Results found

Linked to

	Label	Description
	KAT6A Gene (Entity type)	ENSG00000083168 - lysine acetyltransferase 6A
	ATG4B Gene (Entity type)	ENSG00000168397 - autophagy related 4B cysteine peptidase
	RBCK1 Gene (Entity type)	ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1
	INTS3 Gene (Entity type)	ENSG00000143624 - integrator complex subunit 3
	SIKE1 Gene (Entity type)	ENSG00000052723 - suppressor of IKBKE 1
	PI4KB Gene (Entity type)	ENSG00000143393 - phosphatidylinositol 4-kinase beta
	NISCH Gene (Entity type)	ENSG00000010322 - nischarin
	ARAP1 Gene (Entity type)	ENSG00000186635 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
	EHMT2 Gene (Entity type)	ENSG00000204371 - euchromatic histone lysine methyltransferase 2
	MARK2 Gene (Entity type)	ENSG00000072518 - microtubule affinity regulating kinase 2

KAT6A

Gene (Entity type)

ENSG00000083168 - lysine acetyltransferase 6A

ATG4B

Gene (Entity type)

ENSG00000168397 - autophagy related 4B cysteine peptidase

RBCK1

Gene (Entity type)

ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1

INTS3

Gene (Entity type)

ENSG00000143624 - integrator complex subunit 3

SIKE1

Gene (Entity type)

ENSG00000052723 - suppressor of IKBKE 1

PI4KB

Gene (Entity type)

ENSG00000143393 - phosphatidylinositol 4-kinase beta

NISCH

Gene (Entity type)

ENSG00000010322 - nischarin

ARAP1

Gene (Entity type)

ENSG00000186635 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

EHMT2

Gene (Entity type)

ENSG00000204371 - euchromatic histone lysine methyltransferase 2

MARK2

Gene (Entity type)

ENSG00000072518 - microtubule affinity regulating kinase 2

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.