LY75 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with LY75 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with LY75 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with LY75 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LY75 Up.

Results found

Linked to

	Label	Description
	SPCS1 Gene (Entity type)	ENSG00000114902 - signal peptidase complex subunit 1
	GCAT Gene (Entity type)	ENSG00000100116 - glycine C-acetyltransferase
	PRRC2A Gene (Entity type)	ENSG00000204469 - proline rich coiled-coil 2A
	UROS Gene (Entity type)	ENSG00000188690 - uroporphyrinogen III synthase
	PNPLA6 Gene (Entity type)	ENSG00000032444 - patatin like domain 6, lysophospholipase
	AP2S1 Gene (Entity type)	ENSG00000042753 - adaptor related protein complex 2 subunit sigma 1
	POMZP3 Gene (Entity type)	ENSG00000146707 - POM121 and ZP3 fusion
	IL18RAP Gene (Entity type)	ENSG00000115607 - interleukin 18 receptor accessory protein
	AGPAT1 Gene (Entity type)	ENSG00000204310 - 1-acylglycerol-3-phosphate O-acyltransferase 1
	ARPC4 Gene (Entity type)	ENSG00000241553 - actin related protein 2/3 complex subunit 4

SPCS1

Gene (Entity type)

ENSG00000114902 - signal peptidase complex subunit 1

GCAT

Gene (Entity type)

ENSG00000100116 - glycine C-acetyltransferase

PRRC2A

Gene (Entity type)

ENSG00000204469 - proline rich coiled-coil 2A

UROS

Gene (Entity type)

ENSG00000188690 - uroporphyrinogen III synthase

PNPLA6

Gene (Entity type)

ENSG00000032444 - patatin like domain 6, lysophospholipase

AP2S1

Gene (Entity type)

ENSG00000042753 - adaptor related protein complex 2 subunit sigma 1

POMZP3

Gene (Entity type)

ENSG00000146707 - POM121 and ZP3 fusion

IL18RAP

Gene (Entity type)

ENSG00000115607 - interleukin 18 receptor accessory protein

AGPAT1

Gene (Entity type)

ENSG00000204310 - 1-acylglycerol-3-phosphate O-acyltransferase 1

ARPC4

Gene (Entity type)

ENSG00000241553 - actin related protein 2/3 complex subunit 4

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.