PDE10A Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PDE10A Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PDE10A Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PDE10A Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PDE10A Up.

Results found

Linked to

	Label	Description
	SMAD2 Gene (Entity type)	ENSG00000175387 - SMAD family member 2
	NSA2 Gene (Entity type)	ENSG00000164346 - NSA2 ribosome biogenesis factor
	ATP6V1E1 Gene (Entity type)	ENSG00000131100 - ATPase H+ transporting V1 subunit E1
	TMEM140 Gene (Entity type)	ENSG00000146859 - transmembrane protein 140
	EXOSC8 Gene (Entity type)	ENSG00000120699 - exosome component 8
	ALG5 Gene (Entity type)	ENSG00000120697 - ALG5 dolichyl-phosphate beta-glucosyltransferase
	PCYT2 Gene (Entity type)	ENSG00000185813 - phosphate cytidylyltransferase 2, ethanolamine
	NSL1 Gene (Entity type)	ENSG00000117697 - NSL1 component of MIS12 kinetochore complex
	RNF5 Gene (Entity type)	ENSG00000204308 - ring finger protein 5
	METTL5 Gene (Entity type)	ENSG00000138382 - methyltransferase 5, N6-adenosine

SMAD2

Gene (Entity type)

ENSG00000175387 - SMAD family member 2

NSA2

Gene (Entity type)

ENSG00000164346 - NSA2 ribosome biogenesis factor

ATP6V1E1

Gene (Entity type)

ENSG00000131100 - ATPase H+ transporting V1 subunit E1

TMEM140

Gene (Entity type)

ENSG00000146859 - transmembrane protein 140

EXOSC8

Gene (Entity type)

ENSG00000120699 - exosome component 8

ALG5

Gene (Entity type)

ENSG00000120697 - ALG5 dolichyl-phosphate beta-glucosyltransferase

PCYT2

Gene (Entity type)

ENSG00000185813 - phosphate cytidylyltransferase 2, ethanolamine

NSL1

Gene (Entity type)

ENSG00000117697 - NSL1 component of MIS12 kinetochore complex

RNF5

Gene (Entity type)

ENSG00000204308 - ring finger protein 5

METTL5

Gene (Entity type)

ENSG00000138382 - methyltransferase 5, N6-adenosine

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.