SIRT1 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SIRT1 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SIRT1 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SIRT1 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIRT1 Down.

Results found

Linked to

	Label	Description
	MRPS7 Gene (Entity type)	ENSG00000125445 - mitochondrial ribosomal protein S7
	EIF3I Gene (Entity type)	ENSG00000084623 - eukaryotic translation initiation factor 3 subunit I
	MRPL40 Gene (Entity type)	ENSG00000185608 - mitochondrial ribosomal protein L40
	DCAF10 Gene (Entity type)	ENSG00000122741 - DDB1 and CUL4 associated factor 10
	STN1 Gene (Entity type)	ENSG00000107960 - STN1 subunit of CST complex
	RPL29 Gene (Entity type)	ENSG00000162244 - ribosomal protein L29
	SLC25A12 Gene (Entity type)	ENSG00000115840 - solute carrier family 25 member 12
	UFC1 Gene (Entity type)	ENSG00000143222 - ubiquitin-fold modifier conjugating enzyme 1
	DCTN4 Gene (Entity type)	ENSG00000132912 - dynactin subunit 4
	MIPEP Gene (Entity type)	ENSG00000027001 - mitochondrial intermediate peptidase

MRPS7

Gene (Entity type)

ENSG00000125445 - mitochondrial ribosomal protein S7

EIF3I

Gene (Entity type)

ENSG00000084623 - eukaryotic translation initiation factor 3 subunit I

MRPL40

Gene (Entity type)

ENSG00000185608 - mitochondrial ribosomal protein L40

DCAF10

Gene (Entity type)

ENSG00000122741 - DDB1 and CUL4 associated factor 10

STN1

Gene (Entity type)

ENSG00000107960 - STN1 subunit of CST complex

RPL29

Gene (Entity type)

ENSG00000162244 - ribosomal protein L29

SLC25A12

Gene (Entity type)

ENSG00000115840 - solute carrier family 25 member 12

UFC1

Gene (Entity type)

ENSG00000143222 - ubiquitin-fold modifier conjugating enzyme 1

DCTN4

Gene (Entity type)

ENSG00000132912 - dynactin subunit 4

MIPEP

Gene (Entity type)

ENSG00000027001 - mitochondrial intermediate peptidase

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.